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Hematologic Malignancies

Powering better decisions for you and your patients

Our comprehensive hematology test menu and expertise equip you with detailed reports and deep scientific insights to provide you with the most accurate diagnoses and risk stratifications for your patients.

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Featured tests and services

Acute Lymphoblastic Leukemia (ALL) Tests

Learn more about Acute Lymphoblastic Leukemia (ALL) Tests

Next generation sequencing assays evaluating clinically relevant genes that deliver precise diagnoses and risk stratification for complex hematologic malignancies

Learn more about Labcorp NGS Panels

Labcorp HemePath CASE (Comprehensive Analysis Services & Expertise)


A Labcorp hematopathologist selects medically necessary testing following a rules-based approach, streamlining the testing process to reach a diagnosis and custom treatment plan faster.

Specimen requirements

Learn more about Labcorp HemePath CASE (Comprehensive Analysis Services & Expertise)

Explore Our Test Menu

Our comprehensive menu features more than 450 single analyte and multi-marker tests to provide critical insights you need at every step of the patient journey.

Labcorp is a Children's Oncology Group (COG) Approved Laboratory

Which Labcorp locations perform COG testing?

North Carolina
1912 Alexander Drive
Research Triangle Park, NC 27709
800-345-4363
ax 919-361-7798
 

Connecticut/New York
3 Forest Parkway
Shelton, CT 06484
800-447-5816
Fax 212-258-2143

Arizona
5005 South 40th Street
Phoenix, AZ 85040
800-710-1800
800-481-4151

Which tests are typically ordered on a COG case?
 

ALL MRD by Flow Cytometry
  • Initial Dx: Day 8 (blood)
  • MRD: Day 29 (bone marrow)
Cytogenetics (karyotyping)   
FISH

AML FISH Profile

  • PML/RARA, t(15;17)
  • CBFB, inv(16)
  • RUNX1T1, t(8;21)
  • 5q
  • 7q
  • KMT2A (MLL)

B-ALL Standard Risk Panel

  • BCR/ABL1, t(9;22)
  • Centromere 4
  • Centromere 10
  • Centromere 17
  • KMT2A (MLL)
  • CDKN2A (p16)
  • TCF3 (E2A)
  • ETV6/RUNX1, t(12;21)

B-ALL High Risk Panel

  • Centromere 4
  • Centromere 7
  • Centromere 10
  • KMT2A (MLL)
  • CDKN2A (p16)
  • TCF3 (E2A)
  • ETV6/RUNX1, t(12;21)
  • ABL1 break-apart
  • ABL2 break-apart
  • PDGFRB/CSF1R

ALL MRD by Flow Cytometry

  • Initial Dx: Day 8 (blood)
  • MRD: Day 29 (bone marrow)
Cytogenetics (karyotyping)

FISH 


AML FISH Profile

  • PML/RARA, t(15;17)
  • CBFB, inv(16)
  • RUNX1T1, t(8;21)
  • 5q
  • 7q
  • KMT2A (MLL)

B-ALL Standard Risk Panel

  • BCR/ABL1, t(9;22)
  • Centromere 4
  • Centromere 10
  • Centromere 17
  • KMT2A (MLL)
  • CDKN2A (p16)
  • TCF3 (E2A)
  • ETV6/RUNX1, t(12;21)

B-ALL High Risk Panel

  • Centromere 4
  • Centromere 7
  • Centromere 10
  • KMT2A (MLL)
  • CDKN2A (p16)
  • TCF3 (E2A)
  • ETV6/RUNX1, t(12;21)
  • ABL1 break-apart
  • ABL2 break-apart
  • PDGFRB/CSF1R

All labs performing COG tests are COG-approved and follow COG protocols and standards for COG clinical trials. 

Sponsored Testing Program

Mature woman

Blueprint’s Biomarker Testing Program

No-charge KIT D816V testing for Systemic Mastocytosis provided by Labcorp Oncology for eligible patients through the sponsored testing program from Blueprint Medicines. Early biomarker testing using a non-invasive, highly sensitive, and quantitative KIT D816V test may reduce a patient’s time to diagnosis. 

Meet our team

  • You can trust our team of hematopathology experts

    With decades of experience in hematopathology, our medical staff and laboratory professionals bring deep knowledge and wide-ranging technical expertise. Our experts are also available for consultation and follow-up queries on your patient’s report. 

    Learn More

For more information, reach out to us