Share
PrintTest Details
Cancer Type
Acute lymphocytic leukemia (ALL), Acute myelocytic leukemia (AML), Chronic lymphocytic leukemia (CLL), Chronic myelogenous leukemia (CML), Hematologic malignancies, Leukemia, Lymphoma, Myeloma, Myelodysplastic syndrome (MDS), Myeloproliferative neoplasm (MPN)
Technology Used
FLOW
Turnaround Time
2-3 days
Use
Morphological evaluation of bone marrow is part of the diagnostic workup for suspected hematologic pathology
Special Instructions
Must include clinical/laboratory information, clinical hematological diagnosis, and a recent CBC report.
Test Includes
Includes histologic and cytologic preparation, staining and interpretation of bone marrow smears, biopsies, clot and peripheral blood smears for morphological evaluation, including gross and microscopic examination, decalcification procedure and special stains.
Methodology
Histology, morphology, pathology review
Specimen Requirements
Information on collection, storage, and volume
Specimen
Bone marrow aspirate clot and/or biopsy, bone marrow aspirate smears, and whole blood smears
Volume
2-5 mL, at least 1 cm core of bone marrow (complete specimen), bilateral if for staging of lymphoma
Storage Instructions
Bone marrow core biopsy, clot and/or particles: Store ambient and ship with a cool pack. Bone marrow aspirate smears and/or touch preparations: Store refrigerated and ship with a cool pack.
Causes for Rejection
No marrow obtained
Collection
Smeared slides are prepared and labeled at the bedside by a laboratory technologist. Biopsy and clot are placed in fixative by technologist. Bone marrow smears for enzyme histochemistry must be fixed immediately in 10% neutral buffered formalin, absolute methyl alcohol, or 40% formalin vapor. Fixative container must be labeled with patient's full name, room number, date, and time and the fixative employed.
Related Tests
Find more tests related to this one.
