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Improving Outcomes for Patients with Solid Tumors

OmniSeq® INSIGHT delivers a comprehensive and user-friendly report that offers clinical guidance for more precise and targeted treatment options and clinical trials tailored to your patients within 7-10 days.

Profiling Empowers
You to Make Better Decisions

From a single tumor biopsy, analyzed by advanced next generation sequencing (NGS) technology, OmniSeq INSIGHT identifies treatment options in one comprehensive, easy-to-read report.

We deliver both DNA and RNA fusion sequencing results for 96% of sequenced cases, reflecting our commitment to quality control and robust workflow.

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Genomic profiling

  • 523 Gene NGS Panel
  • Homologous recombination deficiency (HRD)
  • DNA and RNA sequencing
  • Single nucleotide variants (SNVs) – insertions/deletions (indels), copy number alterations (CNAs) and fusions
  • Interrogation of full coding regions
  • HLA genotyping
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Immune Profiling Icon

Immunotherapy biomarkers

  • PD-L1 by immunohistochemistry (IHC)
  • Microsatellite instability (MSI) and tumor mutational burden (TMB)

Labcorp Perspectives Oncology (Episode 5): Redefining ovarian cancer care with biomarkers

 

Why Choose OmniSeq INSIGHT?

1

Single Tumor Biopsy

A single tissue sample provides complete insight into the tumor and its microenvironment.

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2

Pan-Cancer Testing

The report provides comprehensive genomic for all solid tumors.

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3

Treatment Options

A summary of FDA-approved therapies, immunotherapies and eligible clinical trials tailored to your patient’s solid tumor.

Identify Approved Drug Candidates

  • Comprehensive Genomics
    • Detects all four main classes of genomic alterations
    • Fusions / splice variants using RNA-Seq hybrid capture
    • Coverage of clinical practice guideline-recommended biomarkers across solid tumor types
    • Homologous recombination deficiency (HRD) available for patients with ovarian, fallopian tube, and primary peritoneal cancers

Immunotherapy Eligibility

  • Comprehensive Immune Profiling
    • MSI & TMB profiling
    • PD-L1 by IHC

Eligible Clinical Trials

  • List of patient-eligible clinical trials within 200 miles of patient’s physical address1
    • Testing for biomarkers with clinical trial associations

Patient Reports: Concise, Comprehensive & Actionable

Comprehensive Quick-Read Results

Gain actionable insights at a glance with:

  • Clinically significant results
  • Pertinent negative genomic variants
  • A therapy considerations summary
  • Flagged potential cancer-associated hereditary variants

THERAPY CONSIDERATIONS

Start to formulate a plan with:

  • Full-label indications
  • Treatment setting and approval status
  • Guideline evidence
  • Emerging clinical benefits

MARKER DETAILS

See the bigger picture with:

  • Full biomarker details
  • Gene, variant and prevalence information

Clinical Trial Options

Expand your patient’s options with:

  • Number of trial matches per marker
  • Clinical significance for matched trials

The Oncology Dashboard

A dynamic online report for OmniSeq® INSIGHT to power better decisions

View patient-centric Labcorp data and insights where it matters most—right at the point of care. The Oncology Dashboard, as a part of Labcorp Diagnostic AssistantTM, provides clinically actionable information, such as biomarker data and therapeutic recommendations, along with evidence-based guidelines and supporting references. The Oncology Dashboard is accessible through a provider’s electronic health record (EHR) and Labcorp LinkTM.

A dynamic report to support clinical decision-making.

Easy access to Labcorp data to support oncology care

View OmniSeq INSIGHT reports along with core clinical test results for each patient.

Enhanced oncology reports

Precision oncology reports are enriched with interactive digital results. Get related clinical trial information and access to PubMed® articles with supporting evidence.

Dashboard of clinical report

Screenshot of OmniSeq INSIGHT report from The Oncology Dashboard. This screenshot shows detected variants and summaries of potential therapy considerations and clinical trials.
Sample requirements (include pathology report)

Formalin fixed paraffin embedded (FFPE) tissue

  • Resection specimens
  • Needle core biopsy specimens
  • Cell blocks from fine needle aspirates (FNAs)

**Do not submit decalcified specimens, cytology smears or samples from hematologic malignancies**

FFPE block (preferred) or 15 unbaked, positively charged, unstained slides cut a 5 µm plus one H&E
Turnaround time: 7-10 days from sample receipt to report


See test menu for additional information

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Coverage

Labcorp Broad National Coverage

  • In-network with most major health plans
  • 1,600+ contractual relationships with plans, payers and other healthcare organizations

More About OmniSeq INSIGHT

References

1. OmniSeq Knowledgebase - trial radius may be modified for select locations.