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2023 ASCO Annual Meeting
Track: Breast Cancer
#250 Effect of homologous recombination deficient (HRD) breast cancers on a distinct immune marker phenotype by comprehensive genomic and immune profiling (CGIP)
Authors: Heidi Chwan Ko, Sarabjot Pabla, Mary K Nesline, Kyle C Strickland, Rebecca A Previs, Zachary D Wallen, Shengle Zhang, Jeffrey M Conroy, Mark Sausen, Jennifer B Jackson, Kamal S Saini, Scott Wise, Taylor J Jensen, Venkataprasanth P. Reddy, Eric A Severson, Shakti Ramkissoon
Session Title: Breast Cancer - Metastatic
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#251 Comparison of immune microenvironment between primary and metastatic breast tumors
Authors: Heidi Chwan Ko, Sarabjot Pabla, Mary K Nesline, Shipra Gandhi, Kyle C Strickland, Rebecca A Previs, Zachary D Wallen, Shengle Zhang, Jeffrey M Conroy, Mark Sausen, Jennifer B Jackson, Kamal S Saini, Scott Wise, Taylor J Jensen, Venkataprasanth P. Reddy, Eric A Severson, Shakti Ramkissoon
Session Title: Breast Cancer - Metastatic
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#e13085 Reliance of agency-approved and guideline-recommended therapies on surrogate endpoints in triple-negative breast cancer (TNBC)
Authors: Kinisha Gala, Ankit Kalucha, Judith Pérez-Granado, Maria Garcia Requesens, Laura Vidal, Bruno L Larvol, Mark Gramling, Kamal S. Saini
Session Title: Publication Only - Breast Cancer - Metastatic - Triple-Negative
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#e13089 Correlation analysis to assess surrogate endpoints for overall survival (OS) in Triple-Negative Breast Cancer (TNBC)
Authors: Judith Pérez-Granado, Ankit Kalucha, Kinisha Gala, Olga Bodriagova, Laura Vidal, Bruno L Larvol, Mark Gramling, Kamal S. Saini
Session Title: Publication Only - Breast Cancer - Metastatic - Triple-Negative
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Track: Care Delivery and Regulatory Policy
#206a Liquid biopsy-informed precision oncology study to evaluate utility of plasma genomic profiling for therapy selection
Authors: Jessica Tao, Jenna Canzoniero, Maria Fatteh, Timsy Wanchoo, Archana Balan, Rena Xian, Peggy Fitzpatrick, Taxiarchis Botsis, Mark Sausen, Valsamo Anagnostou
Session Title: Care Delivery and Regulatory Policy - Practice Management
#e13630 Decentralized Elements within Oncology Trials: Labcorp Experience
Authors: Alicia Rami, Maria Alcaide, Begoña de las Heras, Laura Vidal, Joanna Pascual, Kurt Lumsden
Session Title: Care Delivery and Regulatory Policy - Technology/Therapeutics
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Track: Developmental Therapeutics
#298 First-in-human phase 1 study of pimicotinib (ABSK021), a CSF-1R inhibitor, in patients with advanced solid tumors
Authors: Gerald Falchook, Yongmei Yin, R. Donald Harvey, Siqing Fu, Weitao Yao, Yanru Qin, Xiaojing Zhang, Qingping Zou, Boyao Shan, Pan Liang, Chen Wang, Wenjia Li, Zehra Nurgul Pamuklar, Yi Pei, Zhiwei Chang, Jiaqiang Wang, Sarina A. Piha-Paul, Manali Bhave, Yan Liang, Jason Timothy Henry
Session Title: Developmental Therapeutics - Molecularly Targeted Agents and Tumor Biology - Small Molecules
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#308 First-in-human (FIH) phase I dose escalation study (Part A) of the first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) roginolisib in patients with advanced cancer and dose confirmation in Uveal Melanoma (Part B)
Authors: Anna Maria Di Giacomo, Federica Santangelo, Giovanni Amato, Elena Simonetti, Jill Graham, Michael M. F. Lahn, Giusy Di Conza, Tracey Hammett, Rebeca Zorrilla, Marco Durini, Ziyang Tan, Lakshmikanth Tadepally, Petter Brodin, Mariaelena Occhipinti, Matteo Simonelli, Carmelo Carlo-Stella, Armando Santoro, Pavlina Spiliopoulou, T.R. Jeffry Evans, Michele Maio
Session Title: Developmental Therapeutics - Molecularly Targeted Agents and Tumor Biology - Small Molecules
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#456 Pan-cancer analysis of IDO1 transcriptome expression and its impact on outcome in patients treated with immune checkpoint inhibitors
Authors: Yu Fujiwara, Shumei Kato, Daisuke Nishizaki, Hirotaka Miyashita, Suzanna Lee, Mary K Nesline, Jeffrey M Conroy, Paul DePietro, Sarabjot Pabla, Scott Lippman, Razelle Kurzrock
Session Title: Developmental Therapeutics - Immunotherapy - Tissue-Based Biomarkers
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#e14641 BTLA transcriptomic expression correlates with high levels of PD-1, PD-L2 and CTLA-4 checkpoints and with its ligand, HVEM, across diverse solid cancers
Authors: Sharon Choi, Razelle Kurzrock, Thomas O'Keefe, Daisuke Nishizaki, Hirotaka Miyashita, Suzanna Lee, Mina Nikanjam, Ramez Nassef Eskander, Hitendra Patel, Gregory P. Botta, Sarabjot Pabla, Mary K Nesline, Jeffrey M. Conroy, Paul DePietro, Jason K. Sicklick, Shumei Kato
Session Title: Publication Only - Developmental Therapeutics - Immunotherapy - Tissue-Based Biomarkers
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#e14561 Implications of GITR expression profile for precision immunotherapeutics
Authors: Peter Moussa, Razelle Kurzrock, Daisuke Nishizaki, Hirotaka Miyashita, Suzanna Lee, Mina Nikanjam, Ramez Eskander, Hitendra Patel, Gregory Botta, Sarabjot Pabla, Mary K Nesline, Jeffrey M Conroy, Paul DePietro, Jason K Sicklick, Shumei Kato
Session Title: Publication Only - Developmental Therapeutics - Immunotherapy - Immunobiology
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#e14669 Relationship between ICOS and ICOS Ligand RNA expression patterns with tumor type, tumor mutational burden, and clinically relevant immune checkpoints
Authors: Mina Nikanjam, Shumei Kato, Daisuke Nishizaki, Donald A. Barkauskas, Sarabjot Pabla, Mary Nesline, Jeffrey M. Conroy, Aung Naing, Razelle Kurzrock
Session Title: Publication Only - Developmental Therapeutics - Immunotherapy - Other Checkpoint Inhibitors (Monotherapy or Combination)
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#e14637 TIGIT transcriptomic expression correlates with high levels of multiple checkpoints across diverse cancers
Authors: Jacob J. Adashek, Shumei Kato, Sarabjot Pabla, Mary Nesline, Jeffrey M. Conroy, Paul DePietro, Razelle Kurzrock
Session Title: Publication Only - Developmental Therapeutics - Immunotherapy - Tissue-Based Biomarkers
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Track: Gynecologic Cancer
#274 Molecular and immune profiling of TP53-mutated ovarian cancers with non-BRCA1/2 homologous recombination gene alterations
Authors: Kyle C Strickland, Rebecca A Previs, Zachary D Wallen, Mary K Nesline, Heidi Chwan Ko, Sarabjot Pabla, Stephanie Hastings, Taylor J Jensen, Prasanth Reddy, Eric A Severson, Shakti Ramkissoon
Session Title: Gynecologic Cancer - Ovarian
Session Type: Poster Session
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#5594 Healthcare access dimensions and uterine cancer survival: A National Cancer Database study
Authors: Mary Katherine Anastasio, Anjali Gupta, Tomi F. Akinyemiju, Rebecca A. Previs
Session Title: Gynecologic Cancer - Ovarian
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#e17548 A Real-World Study of US Patients with Metastatic Ovarian, Fallopian Tube and Peritoneal Cancer (mOFPC) using Integrated Electronic Health Records (EHR) and Claims Datasets
Authors: Avinash PB, Gabriel Funingana, Neeraj Singh, Rohini George, Anna Sowa, Sangavai Chakkrapani, Vandana Priya, Vivek Vaidya, Laura Vidal, Kamal S Saini, Smita Agrawal
Session Title: Gynecologic Cancer - Ovarian
Track: Health Services Research and Quality Improvement
#6506 The impact of single gene testing (SGT) on subsequent comprehensive genomic profiling (CGP) success in community oncology practice for advanced non-small cell lung cancer (NSCLC): Results from a prospective observational reference laboratory testing program
Authors: Mary Nesline, Paul DePietro, Maureen Cooper, Shengle Zhang, Sarah Howarth, Zachary Wallen, Michael Biorn, Kyle Strickland, Rebecca Previs, Heidi Ko, Mark Sausen, Jennifer Jackson, Kamal Saini, Scott Wise, Taylor Jensen, Sarabjot Pabla, Jeffrey Conroy, Prasanth Reddy, Eric Severson, Shakti Ramkissoon
Session Title: Health Services Research and Quality Improvement - Quality of Care/Quality Improvement
Session Type: Oral Abstract
#6590 Site of metastasis and its impact on clinical outcomes in 8 cancer cohorts
Authors: Rohini George, Laura Vidal, Dorota Skalska, Kamal S Saini, et al.
Session Title: Health Services Research and Quality Improvement - Real-World Data/Outcomes
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Track: Lung Cancer
#e21110 TIGIT expression and outcomes in pembrolizumab treated patients with NSCLC
Authors: Maria-Fernanda Senosain, Robert Seager, Erik Van Roey, Shuang Gao, Paul DePietro, Mary Nesline, Durga Dash, Jeffrey Conroy, Stephanie Hastings, Heidi Ko, Kyle Strickland, Rebecca Previs, Eric Severson, Taylor Jensen, Venkataprasanth Reddy, Shakti Ramkissoon, Sarabjot Pabla
Session Title: Lung Cancer - Non-Small Cell Lung Cancer - Advanced/Metastatic Disease
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#e21113 LAG3 landscape in solid tumors and its association with immunotherapy outcomes in non-small cell lung cancer
Authors: R.J. Seager, Maria-Fernanda Senosain, Erik Van Roey, Shuang Gao, Paul DePietro, Mary Nesline, Durga prasad Dash, Jeffrey M Conroy, Heidi Ko; Stephanie Hastings; Kyle C Strickland, Rebecca Ann Previs; Eric Allen Severson; Taylor J Jensen; Prasanth Reddy; Shakti Ramkissoon; Sarabjot Pabla
Session Title: Lung Cancer - Non-Small Cell Lung Cancer - Advanced/Metastatic Disease
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#e21155 Prevalence of KRAS p.G12C mutation in patients with metastatic non-small cell lung cancer in Argentina
Authors: Andrea Mendoza Bertelli, Maria Otero Pizarro, Maria Fernandez, Delfina Dibarbora, Maria Cantarella, Yamil Mahmoud, Romina Girotti, Leandro Guttlein, Isagani Chico, Patrícia Brandalise, Carolina Dutra, Ruben Salanova
Session Title: Lung Cancer - Non-Small Cell Lung Cancer - Advanced/Metastatic Disease
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Track: Prevention, Risk Reduction, and Hereditary Cancer
#e22538 Real-world clinical and genomic analysis of patients with a personal or family history of cancer undergoing germline testing for BRCA1 and BRCA2
Authors: Rebecca A Previs, Heidi Chwan Ko, Zachary D Wallen, Kyle C Strickland, Mary K Nesline, Dagny Noeth, Melissa Hayden, Sabrina Gardner, Ruth A Heim, Taylor J Jensen, Prasanth Reddy, Eric A Severson, Shakti Ramkissoon
Session Title: Publication Only: Prevention, Risk Reduction, and Hereditary Cancer - Germline Genetic Testing
View abstract
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