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HPV (31/33) by ISH

CPT 88342, 88365 (depending on agent tested)

Test Details

Cancer Type

Cervical, Head and neck

Technology Used

ISH

Turnaround Time

2-4 days
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Use

High-risk human papilloma virus subtypes

Special Instructions

Clearly indicate clinical reason for testing provide the following information: differential diagnosis, site of specimen, and clinical information.

Limitations

Only formalin-fixed tissue will be accepted for ISH testing

Methodology

In Situ Hybridization (ISH)

Specimen Requirements

Information on collection, storage, and volume

Specimen

Formalin-fixed paraffin embedded (FFPE) tissue block with Corresponding H&E, and/or unstained slides sectioned from tissue block. Precut slides from paraffin blocks in 5 micron sections.

Volume

0.2 cm x 0.2 cm x 0.2 cm tissue. Minimum of 2 slides per antibod in 5 micron sections

Storage Instructions

Store specimen at room temperature.

Collection

Tissue should be well-fixed in formalin. If alternative fixative is used, it should be noted on the requisition. Unstained Slides: Send all slides within 6 weeks of cutting.
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