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FOLR1 Immunohistochemistry Analysis

CPT 88360

Test Details

Cancer Type

Ovarian

Technology Used

IHC
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Use

VENTANA FOLR1 RxDx Assay is an immunohistochemical assay using mouse monoclonal anti-FOLR1-2.1, intended for use in the assessment of folate receptor alpha (FOLR1) protein in formalin-fixed, paraffin-embedded epithelial ovarian, fallopian tube, or primary peritoneal cancer tissue specimens by light microscopy.

Special Instructions

Note: This test number is used for tracking oncology IHC specimens to the laboratory. Bill codes will be added when testing is complete, based on the processes performed in the laboratory.

Methodology

Immunohistochemistry

References

National Library of Medicine. Mirvetuximab Soravtansine (IMGN853), in Folate Receptor Alpha (FRĪ±) High Recurrent Ovarian Cancer (MIROVA). Accessed December 2022 at https://clinicaltrials.gov/ct2/show/NCT04274426.

Specimen Requirements

Information on collection, storage, and volume

Specimen

Formalin-fixed, paraffin-embedded (FFPE) tissue block

Volume

One paraffin block or five unstained slides sectioned at 4-5 microns, no more than 45 days in age

Minimum Volume

Three unstained slides

Container

Paraffin block or unstained, positive-charged slides

Storage Instructions

Refrigerate; protect from light

Causes for Rejection

Slides sectioned greater than 45 days prior to test request; improper fixation, freezing, thawing, washing, drying, heating, sectioning or contamination with other tissue

Collection

Paraffin block or unstained slides sectioned of no more than 45 days in age

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