Graphical Summary: A consensus-based classification workflow to determine genetically inferred ancestry from comprehensive genomic profiling of patients with solid tumors
February 27, 2025
Key TakeawaysOur GIA calls aligned well with reference populations of inferred ancestries, were highly concordant with SIRE (95%), and could expand upon SIRE by detecting ancestries missing appropriate SIRE groups.Accurate GIA provides essential data to support ancestryaware biomarker research, promote the inclusion of underrepresented groups in clinical studies, and enhance diverse representation in precision clinical trials.
