MYC FISH (See also ALL, Aggressive B-Cell FISH Profiles)

Formalin-fixed, paraffin-embedded (FFPE) block; unstained slides; fresh tissue ; bone marrow; whole blood;

Fixed Paraffin Block with Corresponding H&E: Tissue should be well-fixed in formalin. If alternative fixative is used, it should be noted on the requisition. 0.2 cm x 0.2 cm x 0.2 cm tissue. Fresh Tissue Biopsy: Two (2) pieces 0.2 cm x 0.2 cm x 0.2 cm (8-10 pieces preferred) in transport medium. Do not use transport medium if it turns cloudy, yellow or is beyond the expiration date. Use only pink/orange color media. Refrigerate specimen. Use cold pack for transport. Be sure cold pack is not in direct contact with specimen during transport.

Bone marrow and/or whole blood: green-top (sodium heparin) tube (preferred) or lavender-top (EDTA) tube; FFPE block: paraffin block transport pouch; unstained slides: slide mailer; fresh tissue: RPMI or other transport media

Bone marrow, whole blood, and/or fresh tissue: Store refrigerated and ship with a cool pack. FFPE block and/or unstained slides: Store ambient and ship with a cool pack.

Frozen sample (bone marrow or blood); insufficient sample; broken container; broken slides; cell viability

Store specimen at room temperature. Use cold pack for transport. Be sure cold pack is not in direct contact with specimen during transport. Specimens should be shipped to Integrated Oncology on the day of excision.