FDA-approved CDx; identifies NSCLC patients eligible for crizotinib
Clearly indicate clinical reason for testing provide the following information: differential diagnosis, site of specimen, and clinical information.
Option I: Slides and controls are returned for client interpretation Option II: Slides and controls are returned with an immunostain interpretation Option III: Full surgical pathology consultation (can be ordered with option II)
Use of fixatives other than 10% formalin may not yield equivalent or satisfactory results.
Information on collection, storage, and volume
Formalin-fixed paraffin embedded (FFPE) tissue block with Corresponding H&E, and/or unstained slides sectioned from tissue block. Precut slides from paraffin blocks in 5 micron sections.
0.2 cm x 0.2 cm x 0.2 cm tissue. Minimum of 2 slides per antibod in 5 micron sections
Store specimen at room temperature.
Tissue should be well-fixed in formalin. If alternative fixative is used, it should be noted on the requisition. Unstained Slides: Send all slides within 6 weeks of cutting.; Minimum of 2 slides per antibody. Mount on Poly-L-Lysine-coated or plus (+) slides. Air dry. Do not oven dry.