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ER by IHC

CPT 88342, 88341, 88360; 88361

Test Details

Cancer Type

Breast

Technology Used

IHC

Turnaround Time

2-4 days
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Use

Estrogen receptor; predictive of endocrine therapy response in breast carcinoma; lower female genital tract carcinoma; endometrial stromal neoplasm; soft tissue lesion subset

Special Instructions

Clearly indicate clinical reason for testing provide the following information: differential diagnosis, site of specimen, and clinical information.

Test Includes

Option I: Slides and controls are returned for client interpretation
Option II: Slides and controls are returned with an immunostain interpretation
Option III: Full surgical pathology consultation (can be ordered with option II.)
 

Limitations

Use of fixatives other than 10% formalin may not yield equivalent or satisfactory results.

Methodology

Immunohistochemistry (IHC)

Specimen Requirements

Information on collection, storage, and volume

Specimen

Formalin-fixed paraffin embedded (FFPE) tissue block with Corresponding H&E, and/or unstained slides sectioned from tissue block. Precut slides from paraffin blocks in 5 micron sections.

Volume

0.2 cm x 0.2 cm x 0.2 cm tissue. Minimum of 2 slides per antibod in 5 micron sections

Storage Instructions

Store specimen at room temperature.

Collection

Tissue should be well-fixed in formalin. If alternative fixative is used, it should be noted on the requisition. Unstained Slides: Send all slides within 6 weeks of cutting.; Minimum of 2 slides per antibody. Mount on Poly-L-Lysine-coated or plus (+) slides. Air dry. Do not oven dry.
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