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EGFR by FISH

CPT Contact CPT coding department at 800-222-7566, ext. 6-8400.
Synonyms
  • Brain Cancer
  • Breast Cancer
  • Lung Cancer

Test Details

Cancer Type

Lung

Technology Used

FISH

Turnaround Time

3 - 5 days

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Use

This test is used for confirmation/identification of cancer-related alterations (for lung and brain cancer).

Special Instructions

There will be an additional charge for processing paraffin block samples or for samples that require culture.

Limitations

Molecular mutations or chromosomal alterations not targeted by the probe included in this profile will not be detected. 

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

Methodology

Fluorescence in situ hybridization (FISH)

Specimen Requirements

Information on collection, storage, and volume

Specimen

FFPE slides with tumor, whole blood or paraffin block (acceptable at an additional charge)

Volume

Three slides 4- or 5-micron thick with tumor or 5 mL whole blood

Minimum Volume

Two slides 4- or 5-micron thick on positively charged slides or 1 mL whole blood (Note: Minimum volumes may not allow for repeat testing.)

Container

Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen; no tumor submitted

Collection

Utilize sterile technique and Labcorp transport kits when possible.

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