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Immunohistochemistry (IHC)

CPT 88342 (Immunohistochemistry or immunocytochemistry; each separately identifiable antibody per block, cytologic preparation or hematologic smear; first separately identifiable antibody per slide); 88341 (Immunohistochemistry or immunocytochemistry; each separately identifiable antibody per block, cytologic preparation or hematologic smear; each additional separately identifiable antibody per slide)
Synonyms
  • Carcinoma Stains
  • Germ Cell Profile
  • Immunoperoxidase Stains
  • Lymphoma Markers
  • Mesothelioma Profile
  • Myeloma Profile
  • Thyroid Neoplasm Profile
  • Undifferentiated Tumor Profile

Test Details

Cancer Type

Hematologic malignancies

Technology Used

IHC

Turnaround Time

3 - 7 days

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Use

An extensive list of diagnostic immunohistochemical stains and profiles is available for the diagnosis of poorly differentiated tumors, identity of primary and metastatic tumors, and classification of lymphomas. Refer to the Diagnostic Immunohistochemical Staining Program in the Oncology Appendix online, or contact oncology customer service at 800-345-4363 for an updated list of immunostains.

Special Instructions

Clearly indicate program option being ordered. For program options II and IV, please submit an H&E slide and provide the following information: differential diagnosis, site of specimen, and clinical information. Please direct any questions regarding this test to oncology customer service at 800-345-4363.

Test Includes

• Option I: Slides and controls are returned for your interpretation.

• Option II: Slides and controls are returned with an immunostain interpretation.

• Option IV: Full surgical pathology consultation (can be ordered with option II.)

For a complete list of individual stains and profiles see the Diagnostic Immunohistochemical Staining Program in the Oncology Appendix online.

Limitations

Use of fixatives other than 10% formalin may not yield equivalent or satisfactory results.

Methodology

Immunohistochemistry (IHC)

Related Documents

For more information, please view the literature below.

LabCorp Diagnostic Immunohistochemical Staining Program

    Specimen Requirements

    Information on collection, storage, and volume

    Specimen

    Formalin-fixed, paraffin-embedded (FFPE) tissue and/or slides sectioned from tissue block

    Volume

    One paraffin block and/or two unstained slides sectioned from tissue block for each requested stain

    Container

    Paraffin block transport pouch

    Storage Instructions

    Maintain specimen at room temperature.

    Collection

    Specimen should be fixed in 10% neutral-buffered formalin. Optimum fixation time is 12 to 24 hours, not to exceed 48 hours.

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