PD-L1 by IHC, SP263, TECENTRIQ®

CPT 88360
Synonyms
  • Programmed Death Ligand 1

Test Details

Cancer Type

Lung, Non-small cell lung cancer

Technology Used

IHC

Turnaround Time

6 - 10 days

Use

The PD-L1 (SP263) is a qualitative assay intended for use in the detection of PD-L1 in formalin-fixed, paraffin embedded (FFPE) in non-small-cell lung cancer tissue samples using the Ventana BenchMark Ultra Platform.

Special Instructions

PD-L1 testing will be delayed if the pathology report is not received.

Note: This test number is used for tracking oncology IHC specimens to the laboratory. Bill codes will be added when testing is complete, based on the processes performed in the laboratory.

Methodology

Immunohistochemistry

References

Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med. 1999 Dec;5(12):1365-1369.10581077
Ventana 790-4859, 1014003EN Rev A [package insert]. Ventana; 1-4.

Specimen Requirements

Information on collection, storage, and volume

Specimen

Formalin-fixed, paraffin-embedded (FFPE) tissue block or slides

Volume

At least two unstained slides sectioned at 4 microns, less than two months of sectioning if stored at 15°C to 30°C. Four slides ideal.

Minimum Volume

Two unstained slides at 4 microns, less than two months of sectioning if stored at 15°C to 30°C.

Container

Paraffin block or unstained positive charged slides

Storage Instructions

Refrigerate.

Causes for Rejection

Slides sectioned greater than two months prior to test request and not stored at 15°C to 30°C.

Collection

Paraffin block or unstained slides sectioned if stored at 15°C to 30°C for two months age.