The pan-TRK IHC assay may be used to identify C-terminal protein expression of TRK A, B and C proteins as a surrogate marker of NTRK fusions in solid tumors. Depending on the histologic findings, a positive pan-TRK IHC test may need to be confirmed with an alternative test for NTRK fusions.
Note: This test number is used for tracking oncology IHC specimens to the laboratory. Bill codes will be added when testing is complete, based on the processes performed in the laboratory.
Immunohistochemistry
Information on collection, storage, and volume
Formalin-fixed, paraffin-embedded (FFPE) tissue block or three unstained positive charged slides with sections cut at 3-6 micron thickness
Paraffin block or unstained positive charged slides
Three unstained slides
Paraffin block or unstained positive charged slides
Room temperature
Three unstained positively charged slides with sections cut at 3-6 microns or paraffin block