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pan-TRK IHC

CPT To be determined. Updates will be made when available.
Synonyms
  • NTRK

Test Details

Technology Used

IHC

Use

The pan-TRK IHC assay may be used to identify C-terminal protein expression of TRK A, B and C proteins as a surrogate marker of NTRK fusions in solid tumors. Depending on the histologic findings, a positive pan-TRK IHC test may need to be confirmed with an alternative test for NTRK fusions.

Special Instructions

Note: This test number is used for tracking oncology IHC specimens to the laboratory. Bill codes will be added when testing is complete, based on the processes performed in the laboratory.

Methodology

Immunohistochemistry

Specimen Requirements

Information on collection, storage, and volume

Specimen

Formalin-fixed, paraffin-embedded (FFPE) tissue block or three unstained positive charged slides with sections cut at 3-6 micron thickness

Volume

Paraffin block or unstained positive charged slides

Minimum Volume

Three unstained slides

Container

Paraffin block or unstained positive charged slides

Storage Instructions

Room temperature

Collection

Three unstained positively charged slides with sections cut at 3-6 microns or paraffin block